Publications

Vaidya SP, Li G, Chitwood RA, Li Y, Magee JC. Formation of an expanding memory representation in the hippocampus. Nat Neurosci. 2025 Jul;28(7):1510-1518. doi: 10.1038/s41593-025-01986-3. Epub 2025 Jun 4.PMID: 40467863 

Qian FK, Li Y, Magee JC. Mechanisms of experience-dependent place-cell referencing in hippocampal area CA1. Nat Neurosci. 2025 Jul;28(7):1486-1496. doi: 10.1038/s41593-025-01930-5. Epub 2025 Apr 1.PMID: 40169932 

Li Y, Briguglio JJ, Romani S, Magee JC. Mechanisms of memory-supporting neuronal dynamics in hippocampal area CA3 Cell. 2024 Nov 27;187(24):6804-6819.e21. doi: 10.1016/j.cell.2024.09.041. Epub 2024 Oct 24. PMID: 39454575

Xiao K, Li Y, Chitwood RA, Magee JC. A critical role for CaMKII in behavioral timescale synaptic plasticity in hippocampal CA1 pyramidal neurons. Sci Adv. 2023 Sep 8;9(36):eadi3088. doi: 10.1126/sciadv.adi3088. Epub 2023 Sep 6. PMID: 37672577; PMCID: PMC10482326.

Grienberger C, Magee JC. Entorhinal cortex directs learning-related changes in CA1 representations. Nature. 2022 Nov;611(7936):554-562. doi: 10.1038/s41586-022-05378-6. Epub 2022 Nov 2. PMID: 36323779

Milstein AD, Li Y, Bittner KC, Grienberger C, Soltesz I, Magee JC, Romani S. Bidirectional synaptic plasticity rapidly modifies hippocampal representations. Elife. 2021 Dec 9;10:e73046. doi: 10.7554/eLife.73046. PMID: 34882093 

Magee JC, Grienberger C. Synaptic Plasticity Forms and Functions. Annu Rev Neurosci. 2020 Jul 8;43:95-117. doi: 10.1146/annurev-neuro-090919-022842. Epub 2020 Feb 19. Review.  PMID: 32075520.

Zhao X, Wang Y, Spruston N, Magee JC. Membrane potential dynamics underlying context-dependent sensory responses in the hippocampus. Nat Neurosci. 2020 Jul;23(7):881-891. doi: 10.1038/s41593-020-0646-2. Epub 2020 May 25. PMID: 32451487.

Ranganathan GN, Apostolides PF, Harnett MT, Xu NL, Druckmann S, Magee JC. Active dendritic integration and mixed neocortical network representations during an adaptive sensing behavior. Nat Neurosci. 2018 Nov;21(11):1583-1590. doi: 10.1038/s41593-018-0254-6. Epub 2018 Oct 22. PubMed PMID: 30349100; PubMed Central PMCID: PMC6203624.

Bittner KC, Milstein AD, Grienberger C, Romani S, Magee JC. Behavioral time scale synaptic plasticity underlies CA1 place fields. Science. 2017 Sep 8;357(6355):1033-1036. doi: 10.1126/science.aan3846. PubMed PMID: 28883072; PubMed Central PMCID: PMC7289271.

Grienberger C, Milstein AD, Bittner KC, Romani S, Magee JC. Inhibitory suppression of heterogeneously tuned excitation enhances spatial coding in CA1 place cells. Nat Neurosci. 2017 Mar;20(3):417-426. doi: 10.1038/nn.4486. Epub 2017 Jan 23. PubMed PMID: 28114296.

Apostolides PF, Milstein AD, Grienberger C, Bittner KC, Magee JC. Axonal Filtering Allows Reliable Output during Dendritic Plateau-Driven Complex Spiking in CA1 Neurons. Neuron. 2016 Feb 17;89(4):770-83. doi: 10.1016/j.neuron.2015.12.040. Epub 2016 Jan 28. PubMed PMID: 26833135.

Milstein AD, Bloss EB, Apostolides PF, Vaidya SP, Dilly GA, Zemelman BV, Magee JC. Inhibitory Gating of Input Comparison in the CA1 Microcircuit. Neuron. 2015 Sep 23;87(6):1274-1289. doi: 10.1016/j.neuron.2015.08.025. PubMed PMID: 26402609.

Bittner KC, Grienberger C, Vaidya SP, Milstein AD, Macklin JJ, Suh J, Tonegawa S, Magee JC. Conjunctive input processing drives feature selectivity in hippocampal CA1 neurons. Nat Neurosci. 2015 Aug;18(8):1133-42. doi: 10.1038/nn.4062. Epub 2015 Jul 13. PubMed PMID: 26167906; PubMed Central PMCID: PMC4888374.

Harnett MT, Magee JC, Williams SR. Distribution and function of HCN channels in the apical dendritic tuft of neocortical pyramidal neurons. J Neurosci. 2015 Jan 21;35(3):1024-37. doi: 10.1523/JNEUROSCI.2813-14.2015. PubMed PMID: 25609619; PubMed Central PMCID: PMC4300316.

Druckmann S, Feng L, Lee B, Yook C, Zhao T, Magee JC, Kim J. Structured synaptic connectivity between hippocampal regions. Neuron. 2014 Feb 5;81(3):629-40. doi: 10.1016/j.neuron.2013.11.026. Epub 2014 Jan 9. PubMed PMID: 24412418.

Makara JK, Magee JC. Variable dendritic integration in hippocampal CA3 pyramidal neurons. Neuron. 2013 Dec 18;80(6):1438-50. doi: 10.1016/j.neuron.2013.10.033. PubMed PMID: 24360546; PubMed Central PMCID: PMC3878388.

Harnett MT, Xu NL, Magee JC, Williams SR. Potassium channels control the interaction between active dendritic integration compartments in layer 5 cortical pyramidal neurons. Neuron. 2013 Aug 7;79(3):516-29. doi: 10.1016/j.neuron.2013.06.005. PubMed PMID: 23931999; PubMed Central PMCID: PMC3847879.

Xu NL, Harnett MT, Williams SR, Huber D, O’Connor DH, Svoboda K, Magee JC. Nonlinear dendritic integration of sensory and motor input during an active sensing task. Nature. 2012 Dec 13;492(7428):247-51. doi: 10.1038/nature11601. Epub 2012 Nov 11. PubMed PMID: 23143335.

Harnett MT, Makara JK, Spruston N, Kath WL, Magee JC. Synaptic amplification by dendritic spines enhances input cooperativity. Nature. 2012 Nov 22;491(7425):599-602. doi: 10.1038/nature11554. Epub 2012 Oct 28. PubMed PMID: 23103868; PubMed Central PMCID: PMC3504647.

Bittner KC, Andrasfalvy BK, Magee JC. Ion channel gradients in the apical tuft region of CA1 pyramidal neurons. PLoS One. 2012;7(10):e46652. doi: 10.1371/journal.pone.0046652. Epub 2012 Oct 3. PubMed PMID: 23056387; PubMed Central PMCID: PMC3463549.

Royer S, Zemelman BV, Losonczy A, Kim J, Chance F, Magee JC, Buzsáki G. Control of timing, rate and bursts of hippocampal place cells by dendritic and somatic inhibition. Nat Neurosci. 2012 Mar 25;15(5):769-75. doi: 10.1038/nn.3077. PubMed PMID: 22446878; PubMed Central PMCID: PMC4919905.

Magee JC. Observations on clustered synaptic plasticity and highly structured input patterns. Neuron. 2011 Dec 22;72(6):887-8. doi: 10.1016/j.neuron.2011.12.009. PubMed PMID: 22196323.

Kim J, Zhao T, Petralia RS, Yu Y, Peng H, Myers E, Magee JC. mGRASP enables mapping mammalian synaptic connectivity with light microscopy. Nat Methods. 2011 Dec 4;9(1):96-102. doi: 10.1038/nmeth.1784. PubMed PMID: 22138823; PubMed Central PMCID: PMC3424517.

Losonczy A, Zemelman BV, Vaziri A, Magee JC. Network mechanisms of theta related neuronal activity in hippocampal CA1 pyramidal neurons. Nat Neurosci. 2010 Aug;13(8):967-72. doi: 10.1038/nn.2597. Epub 2010 Jul 18. PubMed PMID: 20639875; PubMed Central PMCID: PMC2921679.

Royer S, Zemelman BV, Barbic M, Losonczy A, Buzsáki G, Magee JC. Multi-array silicon probes with integrated optical fibers: light-assisted perturbation and recording of local neural circuits in the behaving animal. Eur J Neurosci. 2010 Jun;31(12):2279-91. doi: 10.1111/j.1460-9568.2010.07250.x. Epub 2010 Jun 7. PubMed PMID: 20529127; PubMed Central PMCID: PMC2954764.

Makara JK, Losonczy A, Wen Q, Magee JC. Experience-dependent compartmentalized dendritic plasticity in rat hippocampal CA1 pyramidal neurons. Nat Neurosci. 2009 Dec;12(12):1485-7. doi: 10.1038/nn.2428. Epub 2009 Nov 8. PubMed PMID: 19898470.

Varga V, Losonczy A, Zemelman BV, Borhegyi Z, Nyiri G, Domonkos A, Hangya B, Holderith N, Magee JC, Freund TF. Fast synaptic subcortical control of hippocampal circuits. Science. 2009 Oct 16;326(5951):449-53. doi: 10.1126/science.1178307. PubMed PMID: 19833972.

Takahashi H, Magee JC. Pathway interactions and synaptic plasticity in the dendritic tuft regions of CA1 pyramidal neurons. Neuron. 2009 Apr 16;62(1):102-11. doi: 10.1016/j.neuron.2009.03.007. PubMed PMID: 19376070.

Losonczy A, Makara JK, Magee JC. Compartmentalized dendritic plasticity and input feature storage in neurons. Nature. 2008 Mar 27;452(7186):436-41. doi: 10.1038/nature06725. PubMed PMID: 18368112.

Ji N, Magee JC, Betzig E. High-speed, low-photodamage nonlinear imaging using passive pulse splitters. Nat Methods. 2008 Feb;5(2):197-202. doi: 10.1038/nmeth.1175. Epub 2008 Jan 20. PubMed PMID: 18204458.

Gasparini S, Losonczy A, Chen X, Johnston D, Magee JC. Associative pairing enhances action potential back-propagation in radial oblique branches of CA1 pyramidal neurons. J Physiol. 2007 May 1;580(Pt.3):787-800. doi: 10.1113/jphysiol.2006.121343. Epub 2007 Feb 1. PubMed PMID: 17272353; PMCID: PMC2075451.

Losonczy A, Magee JC. Integrative properties of radial oblique dendrites in hippocampal CA1 pyramidal neurons. Neuron. 2006 Apr 20;50(2):291-307. doi: 10.1016/j.neuron.2006.03.016. PubMed PMID: 16630839; NIHMSID:NIHMS35484.

Gasparini S, Magee JC. State-dependent dendritic computation in hippocampal CA1 pyramidal neurons. J Neurosci. 2006 Feb 15;26(7):2088-100. doi: 10.1523/JNEUROSCI.4428-05.2006. PubMed PMID: 16481442; PubMed Central PMCID: PMC6674927.

McDermott CM, Hardy MN, Bazan NG, Magee JC. Sleep deprivation-induced alterations in excitatory synaptic transmission in the CA1 region of the rat hippocampus. J Physiol. 2006 Feb 1;570(Pt 3):553-65. doi: 10.1113/jphysiol.2005.093781. Epub 2005 Dec 1. PubMed PMID: 16322058; PubMed Central PMCID: PMC1479879.

Magee JC, Johnston D. Plasticity of dendritic function. Curr Opin Neurobiol. 2005 Jun;15(3):334-42. doi: 10.1016/j.conb.2005.05.013. Review. PubMed PMID: 15922583.

Gasparini S, Migliore M, Magee JC. On the initiation and propagation of dendritic spikes in CA1 pyramidal neurons. J Neurosci. 2004 Dec 8;24(49):11046-56. doi: 10.1523/JNEUROSCI.2520-04.2004. PubMed PMID: 15590921; PubMed Central PMCID: PMC6730267.

Andrásfalvy BK, Magee JC. Changes in AMPA receptor currents following LTP induction on rat CA1 pyramidal neurones. J Physiol. 2004 Sep 1;559(Pt 2):543-54. doi: 10.1113/jphysiol.2004.065219. Epub 2004 Jul 2. PubMed PMID: 15235093; PubMed Central PMCID: PMC1665120.

McDermott CM, LaHoste GJ, Chen C, Musto A, Bazan NG, Magee JC. Sleep deprivation causes behavioral, synaptic, and membrane excitability alterations in hippocampal neurons. J Neurosci. 2003 Oct 22;23(29):9687-95. PubMed PMID: 14573548; PubMed Central PMCID: PMC6740462.

Andrásfalvy BK, Smith MA, Borchardt T, Sprengel R, Magee JC. Impaired regulation of synaptic strength in hippocampal neurons from GluR1-deficient mice. J Physiol. 2003 Oct 1;552(Pt 1):35-45. doi: 10.1113/jphysiol.2003.045575. Epub 2003 Jul 23. PubMed PMID: 12878757; PubMed Central PMCID: PMC2343312.

Smith MA, Ellis-Davies GC, Magee JC. Mechanism of the distance-dependent scaling of Schaffer collateral synapses in rat CA1 pyramidal neurons. J Physiol. 2003 Apr 1;548(Pt 1):245-58. doi: 10.1113/jphysiol.2002.036376. Epub 2003 Feb 21. PubMed PMID: 12598591; PubMed Central PMCID: PMC2342790.

Magee JC. A prominent role for intrinsic neuronal properties in temporal coding. Trends Neurosci. 2003 Jan;26(1):14-6. doi: 10.1016/s0166-2236(02)00012-7. Review. PubMed PMID: 12495857.

Gasparini S, Magee JC. Phosphorylation-dependent differences in the activation properties of distal and proximal dendritic Na+ channels in rat CA1 hippocampal neurons. J Physiol. 2002 Jun 15;541(Pt 3):665-72. doi: 10.1113/jphysiol.2002.020503. PubMed PMID: 12068031; PubMed Central PMCID: PMC2290356.